İki Yaşındaki Kız Çocuğunda Levetirasetama Bağlı Akut Rabdomiyoliz

Levetiracetam is one of the safest drugs which used for treatment focal and generalized seizures during childhood. Until now, few patients have been reported with diagnosis acute rhabdomyolysis due to levetiracetam our case youngest patient in literature. Two-year old girl followed atypical Rett syndrome (CDKL 5 deficiency) was admitted hospital pneumonia respiratory insufficiency. She receiving intravenous antibiotics therapy. During follow-up, increase creatine kinase levels continued, hydration alkalinization added on As we could not find any etiology explaining raising patient, thought be cause withdrawn. After discontinuation levetiracetam, began decline within 24 h returned normal week. Levetiracetam-induced quite rare but a life-threatening condition should kept mind especially The renal function tests all first week Early supportive therapy very important order prevent kidney injury. CDKL deficiency can protective factor might injury more research needed about this topic.